Acetone → HCID 178444030, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 42 but using 3.4 g. sodium in 500 ml. dry acetone, 24.7 g. heptanamidine hydrochloride, and 27.2 g. 4-(methylthio)phenyl isothiocyanate (m.p. 60°-61°C.; prepared from 4-methylthioaniline) in 120 ml. dry acetone there was obtained 1-[4-(methylthio)phenyl]-3-(heptanimidoyl)-2-thiourea, m.p. 100°-101°C. (from benzene-n-pentane); hydrochloride (43.5 g.), m.p. 181°-182°C.

Provenance & Evidence