HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 178444016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 1-Isothiocyanato-3-(trifluoromethyl)benzene | HCID 137232 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Heptanimidamide hydrochloride | HCID 14144282 | — |
| Solvent | Benzene hexane | HCID 110624 | — |
| Product | HCID 178444016 | HCID 178444016 | — |
Reaction Steps
Following a procedure similar to that described in Example 42 and using 3.4 g. sodium in 350 ml. dry acetone, 24.7 g. heptanamidine hydrochloride, and 30.4 g. 3-(trifluoromethyl)phenyl isothiocyanate [b.p. 50°-52°C./0.05-0.08 mm.; prepared from 3-(trifluoromethyl)aniline] in 150 ml. dry acetone there was obtained 1-[3-(trifluoromethyl)phenyl]-3-(heptanimidoyl)-2-thiourea, m.p. 105°-107°C. (from benzene-n-hexane); hydrochloride (34.4 g.), m.p. 154°-155°C. (from acetonitrile).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984467 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-e532201754714fbb9c8d3d20b22306e8 |
| Source note | uspto-grants-1976_10 |