HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20358452, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Acetic acid, 6,7-dichloro-2-isopropyl-1-oxo-5-indanyloxy- | HCID 40499 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20358452 | HCID 20358452 | — |
Reaction Steps
To a solution of (1-oxo-2-isopropyl-6,7-dichloro-5-indanyloxy)acetic acid (3.17 g., 0.01 mole) and sodium hydroxide (0.5 g., 0.0125 mole) in water (90 ml.) is added aqueous formaldehyde (1 ml., 0.012 mole). The resulting solution is stirred at 20°-25° C. for 41/2 days and acidified with hydrochloric acid. There is obtained 2.5 g. of (1-oxo-2-hydroxymethyl-2-isopropyl-6,7-dichloro-5-indanyloxy)acetic acid which melts at 200°-202° C. after recrystallization from ethanol-water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984465 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-f338d44651cf4cd6a82940c59b9ef1bc |
| Source note | uspto-grants-1976_10 |