Thiophosgene → HCID 56618003, compound

Participants

Reaction Steps

Following the procedure of Examples 1A and 2A, 21.6 g. of 2-amino-3-methylpyridine, 42 g. of calcium carbonate and 24.5 g. of thiophosgene are converted into 3-methyl-2-pyridylisothiocyanate with a b.p. of 84° C. at 0.5 mm. of Hg. 10 G. of the freshly distilled isothiocyanate is dissolved in 100 ml. of acetonitrile and the reaction mixture carried out as in Examples 1B and 2B affording 9-methyl-3-(3-methyl-2-pyridyl) pyrido (1,2-a) 1,3,5-triazine-2,4-dithione m.p. 131°-132° C.

Provenance & Evidence