HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 21509168, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 12500217 | HCID 12500217 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 21509168 | HCID 21509168 | — |
Reaction Steps
To ten grams of 2-amino-3-(p-chlorophenyl)-1-methylindole hydrochloride in 80 ml. of pyridine, 5.4 ml. acetic anhydride are added under stirring at 20°-25° C. After five hours the pyridine is distilled off in vacuo at 40°-45° C and the oily residue solidifies with water. The product is crystallized from methanol. Yield 7.9 g. M.p. 196°-197° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984563 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-e8339ad0d91846caa8abd51562b92fea |
| Source note | uspto-grants-1976_10 |