Ammonium Hydroxide → HCID 21509194, compound

HRID 1287508Notes

Reaction equation

HRID 1287508 reaction equation
[OH-].[NH4+:2].Cl.[C:4]([CH2:9][N:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:12]([CH3:20])([CH3:19])[C:11]1=[NH:21])(OCC)=[O:5]>C(O)C>[C:4]([CH2:9][N:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:12]([CH3:20])([CH3:19])[C:11]1=[NH:21])(=[O:5])[NH2:2]

Participants

4

Reactant 2

HCID 14923Ammonium HydroxideHCID 21509222HCID 21509222, compound

Product 1

HCID 21509194HCID 21509194, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 25 ml. of 32% ammonium hydroxide and 15 ml. of ethanol, 4.5 g. of 1-carbethoxymethyl-3,3-dimethyl-2-iminoindoline hydrochloride are added. After 15 hours the reaction mixture is evaporated to dryness and the residue is crystallized from chloroform giving 3,5 g. of the product of the title, melting at 167°-173° C.

Workup

  1. customAfter 15 hours the reaction mixture is evaporated to dryness
  2. customthe residue is crystallized from chloroform giving 3,5 g

Sources & evidence

ORD record
ord-8a416bc6dc9444e1a16c8c88101b6a46
Source dataset
uspto-grants-1976_10
Patent number
US03984563

Reaction notes

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