Hydrochloric Acid → HCID 21509169, compound

HRID 1287509Notes

Reaction equation

HRID 1287509 reaction equation
[ClH:1].[NH2:2][C:3]1[N:4]([CH3:21])[C:5]2[C:10]([C:11]=1[C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2>[Pd].C(O)C>[ClH:1].[NH2:2][C:3]1[N:4]([CH3:21])[C:5]2[C:10]([C:11]=1[C:12]1[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 134869191-Methyl-3-(4-nitrophenyl)-1H-indol-2-amine

Product 1

HCID 21509169HCID 21509169, compoundYield 53%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The compound is obtained by hydrogenating at room temperature and atmospheric pressure in the presence 10% Pd on charcoal an ethanol solution of the hydrochloride of 2-amino-1-methyl-3-(p-nitrophenyl) indole. Yield 53%, m.p. 258°-261° C.

Workup

  1. customThe compound is obtained
  2. customby hydrogenating at room temperature

Sources & evidence

ORD record
ord-1eb83efcc27345f381510b9992d14e6c
Source dataset
uspto-grants-1976_10
Patent number
US03984563

Reaction notes

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