7-Aminocephalosporanic acid → HCID 70603084, compound
Reaction equation
CC(O[CH2:5][C:6]1[CH2:15][S:14][C@@H:9]2[C@H:10]([NH2:13])[C:11](=[O:12])[N:8]2[C:7]=1[C:16]([OH:18])=[O:17])=O.[SH:19][C:20]1[N:24]([CH3:25])[CH:23]=[N:22][N:21]=1>>[NH2:13][CH:10]1[C:11](=[O:12])[N:8]2[C:7]([C:16]([OH:18])=[O:17])=[C:6]([CH2:5][S:19][C:20]3[N:24]([CH3:25])[CH:23]=[N:22][N:21]=3)[CH2:15][S:14][C@H:9]12Participants
3
Procedure
7-Amino-3-(4-methyl-1,2,4-triazol-3-ylthiomethyl)-3-cephem-4-carboxylic acid was prepared from 7-ACA and 3-mercapto-4-methyl-1,2,4-triazole according to the first paragraph of Example 1.
Sources & evidence
- ORD record
- ord-666386f8eeb04d17b628f93a53a7e360
- Source dataset
- uspto-grants-1976_10
- Patent number
- US03985739
Reaction notes
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