HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → 5-Dimethylsulphamyl-3-nitro-4-phenoxy-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 4-Chloro-5-dimethylsulphamyl-3-nitro-benzoic acid | HCID 21506054 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-Dimethylsulphamyl-3-nitro-4-phenoxy-benzoic acid | HCID 21505999 | — |
Reaction Steps
A mixture of 4-chloro-5-dimethylsulphamyl-3-nitro-benzoic acid (3.08 g), a phenol (2g), sodium hydrogen carbonate (3.4 g), and water (20 ml) was heated at 90° C for 8 hours. Then water (40 ml) was added and, after cooling, the 5-dimethylsulphamyl-3-nitro-4-phenoxy-benzoic acid was precipitated by acidification with 4N hydrochloric acid. After isolation by filtration and several recrystallizations from ethanol, the said compound was obtained with a melting point of 224°-226° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985777 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-6fb0572b0a83466b9833bd5245d341fa |
| Source note | uspto-grants-1976_10 |