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HRID1287712

反应详情

EQUATION

反应方程式

HRID 1287712 的结构方程式

REACTANTS

反应物

3
结构：Oc1ccccc1
HCID996

Phenol

C6H6O

结构：O=C([O-])O.[Na+]
HCID516892

Sodium Bicarbonate

CHNaO3

结构：CN(C)S(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl
HCID21506054

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)S(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Oc1ccccc1
HCID21505999

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

2 次

PROCEDURE

实验过程

A mixture of 4-chloro-5-dimethylsulphamyl-3-nitro-benzoic acid (3.08 g), a phenol (2g), sodium hydrogen carbonate (3.4 g), and water (20 ml) was heated at 90° C for 8 hours. Then water (40 ml) was added and, after cooling, the 5-dimethylsulphamyl-3-nitro-4-phenoxy-benzoic acid was precipitated by acidification with 4N hydrochloric acid. After isolation by filtration and several recrystallizations from ethanol, the said compound was obtained with a melting point of 224°-226° C.

WORKUP

后处理

  1. temperatureafter cooling
  2. customthe 5-dimethylsulphamyl-3-nitro-4-phenoxy-benzoic acid was precipitated by acidification with 4N hydrochloric acid
  3. filtrationAfter isolation by filtration and several recrystallizations from ethanol
  4. customthe said compound was obtained with a melting point of 224°-226° C.