HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Toluidine → 3-Nitro-5-sulphamyl-4-(m-toluidino)-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Toluidine | HCID 7934 | — |
| Reactant | 4-Chloro-3-nitro-5-sulphamoylbenzoic acid | HCID 89893 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Nitro-5-sulphamyl-4-(m-toluidino)-benzoic acid | HCID 21505988 | — |
Reaction Steps
A mixture of 4-chloro-3-nitro-5-sulphamyl-benzoic acid (28 g), m-toluidine (32.2 g), and water (500 ml) was refluxed for 3 hours. After cooling and acidification with 2N hydrochloric acid, the precipitated 3-nitro-5-sulphamyl-4-(m-toluidino)-benzoic acid was collected by suction, washed with water, and recrystallized from isopropanol. After drying at 115° C in vacuo, the melting point was 256°-259° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985777 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-8129aa93cbf54796ac685ecaefc3577b |
| Source note | uspto-grants-1976_10 |