Hydrochloric Acid → HCID 21506032, compound

HRID 1287761Notes

Reaction equation

HRID 1287761 reaction equation
C([O:5][C:6](=[O:35])[C:7]1[CH:12]=[C:11]([S:13](=[O:16])(=[O:15])[NH2:14])[C:10]([O:17][C:18]2[CH:23]=[CH:22][C:21]([O:24][CH2:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[CH:20][CH:19]=2)=[C:9]([N+:32]([O-:34])=[O:33])[CH:8]=1)CCC.Cl>[OH-].[Na+]>[CH2:25]([O:24][C:21]1[CH:20]=[CH:19][C:18]([O:17][C:10]2[C:11]([S:13](=[O:15])(=[O:16])[NH2:14])=[CH:12][C:7]([C:6]([OH:35])=[O:5])=[CH:8][C:9]=2[N+:32]([O-:34])=[O:33])=[CH:23][CH:22]=1)[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86733770HCID 86733770, compound

Product 1

HCID 21506032HCID 21506032, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A solution of n-butyl-4-(4-benzyloxyphenoxy)-3-nitro-5-sulphamyl-benzoate (7.3 g) in 1N sodium hydroxide (120 ml) was heated on a steam bath for 45 minutes. After cooling and acidification by addition of 4N hydrochloric acid, the precipitated 4-(4-benzyloxyphenoxy)-3-nitro-5-sulphamyl-benzoic acid was isolated by filtration and recrystallized from aqueous ethanol. After drying, the compound was obtained with a melting point of 247° C.

Workup

  1. temperatureAfter cooling

Sources & evidence

ORD record
ord-6e5a947dc35043dbbfd7f9e9dd7e412d
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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