Hydrochloric Acid → HCID 21506049, compound

HRID 1287781Notes

Reaction equation

HRID 1287781 reaction equation
C([O:3][C:4](=[O:26])[C:5]1[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]([O:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[C:7]([NH:22][CH2:23][CH:24]=[CH2:25])[CH:6]=1)C.O.Cl>[OH-].[Na+]>[CH2:23]([NH:22][C:7]1[CH:6]=[C:5]([CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]=1[O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:4]([OH:26])=[O:3])[CH:24]=[CH2:25]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 21506073HCID 21506073, compound

Product 1

HCID 21506049HCID 21506049, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Ethyl-3-allylamino-4-phenoxy-5-sulphamyl-benzoate (1 g) was dissolved in 1N sodium hydroxide (15 ml) and left standing at room temperature for 24 hours. Then water (5 ml) was added, and the pH was adjusted to 3 by the addition of 4N hydrochloric acid. The precipitated 3-allylamino-4-phenoxy-5-sulphamyl-benzoic acid was collected and dried. The melting point was 233°-225° C.

Workup

  1. waitleft
  2. customThe precipitated 3-allylamino-4-phenoxy-5-sulphamyl-benzoic acid was collected
  3. customdried

Sources & evidence

ORD record
ord-6b6909e32c024726872f7817bbfb4b50
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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