HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 3-benzylamino-5-sulphamyl-4-(m-trifluoromethylphenoxy)-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Benzoic acid,3-amino-5-(aminosulfonyl)-4-[3-(trifluoromethyl)phenoxy]- | HCID 21312196 | — |
| Product | Ethyl 3-benzylamino-5-sulphamyl-4-(m-trifluoromethylphenoxy)-benzoate | HCID 21506121 | — |
Reaction Steps
A mixture of 3-amino-5-sulphamyl-4-(m-trifluoromethylphenoxy)-benzoic acid (1.82 g), benzyl bromide (2 g), and anhydrous ethanol (15 ml) was refluxed for 7 hours. The solution was cooled, and the precipitated ethyl 3-benzylamino-5-sulphamyl-4-(m-trifluoromethylphenoxy)benzoate was collected by suctin. After recrystallizatin from ethanol, the melting point was 166°-168° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985777 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-4c829db2a7a1414f97beceda6d69447f |
| Source note | uspto-grants-1976_10 |