Butylamine → HCID 21506110, compound

HRID 1287800Notes

Reaction equation

HRID 1287800 reaction equation
Cl[C:2]1[C:10]([S:11](=[O:14])(=[O:13])[NH2:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].[CH2:18]([NH2:22])[CH2:19][CH2:20][CH3:21]>O>[CH2:18]([NH:22][C:2]1[C:10]([S:11](=[O:14])(=[O:13])[NH2:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16])[CH2:19][CH2:20][CH3:21]

Participants

4

Reactant 2

HCID 8007ButylamineHCID 898934-Chloro-3-nitro-5-sulphamoylbenzoic acid

Product 1

HCID 21506110HCID 21506110, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
90 °C

Procedure

A mixture of 4-chloro-3-nitro-5-sulphamyl-benzoic acid (8.4 g), n-butylamine (8.7 g), and water (25 ml) was stirred at 90° C for 1.5 hours. After cooling, the pH was adjusted to pH 2, and the precipitated 4-butylamino-3-nitro-5-sulphamyl-benzoic acid was collected by filtration. After several recrystallizations from aqueous methanol the melting point was 192.5° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe precipitated 4-butylamino-3-nitro-5-sulphamyl-benzoic acid was collected by filtration
  3. customAfter several recrystallizations from aqueous methanol the melting point was 192.5° C.

Sources & evidence

ORD record
ord-02b362a9135c42a289e261d912183610
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

Loading…