Ammonia → HCID 68141669, compound

HRID 1287826Notes

Reaction equation

HRID 1287826 reaction equation
[CH:1]1[C:12]2=[C:13]3[C:4](=[CH:5][CH:6]=[CH:7][C:8]3=[N:9][C:10]3[N:11]2CO[CH:16]=3)[C:3](=O)[CH:2]=1.N.[ClH:19].[C:20](=[O:37])([O:22]CC1NC2C=CC=C3C=2C(N=1)=CC=C3)[NH2:21]>C(COC)OC>[ClH:19].[NH:11]1[C:12]2=[C:13]3[C:4](=[CH:3][CH:2]=[CH:1]2)[CH:5]=[CH:6][CH:7]=[C:8]3[N:9]=[C:10]1[CH2:16][NH:21][C:20](=[O:22])[OH:37]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 21506585HCID 21506585, compoundHCID 21506588HCID 21506588, compound

Product 1

HCID 68141669HCID 68141669, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

A sample of 1H, 3H-oxazolo[3,4-a]perimidine-3-one is dissolved in dimethoxyethane and is treated with excess conc. ammonia. The separated solid, (2-perimidyl)methyl carbamate, is filtered, dissolved in ethanol and treated with hydrochloric acid to give the acid addition salt, (2-perimidyl)methyl carbamate hydrochloride, m.p. 240° (dec.).

Workup

  1. filtrationThe separated solid, (2-perimidyl)methyl carbamate, is filtered
  2. dissolutiondissolved in ethanol
  3. additiontreated with hydrochloric acid
  4. customto give

Sources & evidence

ORD record
ord-d48920d9dcda4bfc812e0772d8a71976
Source dataset
uspto-grants-1976_10
Patent number
US03985880

Reaction notes

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