反应详情

5-Nitro-2-(3-pyridinyl)benzothiazole 11.2 g, 0.044 mole, is dissolved in 45 cc of concentrated HCl. SnCl2, 35 g, in 45 cc of concentrated HCl is added, and the resulting mixture heated for 1 hour on a steam bath. After cooling, the precipitate is filtered, washed in cold HCl and neutralized in cold NaOh solution. The amine is filtered, washed with H2O and dried to yield 8.0 g of product m.p. 189°-196°.

1. temperaturethe resulting mixture heated for 1 hour on a steam bath
2. temperatureAfter cooling
3. filtrationthe precipitate is filtered
4. washwashed in cold HCl and neutralized in cold NaOh solution
5. filtrationThe amine is filtered
6. washwashed with H2O
7. customdried