HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → HCID 53680523, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | N-[2-(Benzyloxy)-5-(pyridine-2-carbonyl)phenyl]acetamide | HCID 53916260 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 53680523 | HCID 53680523 | — |
Reaction Steps
An anhydrous benzene solution of 3-acetamido-4-benzyloxyphenyl 2-pyridyl ketone is heated at reflux with sodium until a suspension is formed. To this suspension is added sulfuryl chloride in benzene and the resulting mixture is filtered to remove sodium chloride. The filtrate is evaporated to give 4-benzyloxy-3-(N-chlorosulfonylacetamido)phenyl 2-pyridyl ketone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985887 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-d60b15a2f1a14c9589b857e64d02e222 |
| Source note | uspto-grants-1976_10 |