HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzaldehyde → HCID 53689253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzaldehyde | HCID 7726 | — |
| Reactant | beta-Aminobeta-ethoxyacrylic acid ethyl ester | HCID 278451 | — |
| Product | HCID 53689253 | HCID 53689253 | 56% |
Reaction Steps
Boiling a solution of 7.1 g of 4-chlorobenzaldehyde and 15.9 g of 3-amino-3-ethoxyacrylic acid ethyl ester in 50 ml of alcohol for 8 hours yields 2-amino-4-(4-chlorophenyl)-6-ethoxy-4,5-dihydropyridine-3,5-dicarboxylic acid diethyl ester of melting point 130°-132° C (ethyl acetate/petroleum ether). Yield: 56% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985886 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-55249c5eee6b4d38bccb83e0af41f745 |
| Source note | uspto-grants-1976_10 |