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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1287883Generated: October 30, 2026

4-Chloro-6-fluoro-2-methylquinoline → 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

https://huagongshe.com/reaction/1287883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-6-fluoro-2-methylquinolineHCID 87694—
CatalystRhodiumHCID 23948—
Product6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinolineHCID 591684—

Reaction Steps

4-Chloro-6-fluoroquinaldine was reduced with rhodium on carbon to give 6-fluoro-2-methyltetrahydroquinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03985882
Source datasetuspto-grants-1976_10
ORD IDord-50d02a222b7c477d87f05445bf215990
Source noteuspto-grants-1976_10