4-Chloro-6-fluoro-2-(trifluoromethyl)quinoline → HCID 21445341, compound

HRID 1287889Notes

Reaction equation

HRID 1287889 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:12])[CH:10]=2)[N:5]=[C:4]([C:13]([F:16])([F:15])[F:14])[CH:3]=1>[Pt]>[F:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[NH:5][CH:4]([C:13]([F:15])([F:14])[F:16])[CH2:3][CH2:2]2

Participants

3

Reactant 1

HCID 27365914-Chloro-6-fluoro-2-(trifluoromethyl)quinoline

Product 1

HCID 21445341HCID 21445341, compound

Reagents, catalysts & solvents 1

HCID 23939PlatinumCatalyst

Procedure

4-Chloro-6-fluoro-2-trifluoromethylquinoline was reduced with platinum on carbon to give 6-fluoro-2-trifluoromethyltetrahydroquinoline.

Sources & evidence

ORD record
ord-21da84ba9e674d2dad43eab746ee7f7e
Source dataset
uspto-grants-1976_10
Patent number
US03985882

Reaction notes

Loading…