Hydrochloric Acid → HCID 21506818, compound
Reaction equation
CC1(C)C[O:5][C:4]([C:7]2[CH:12]=[C:11]3[O:13][CH2:14][O:15][C:10]3=[CH:9][C:8]=2[C:16]2([OH:23])[CH2:21][CH2:20][N:19]([CH3:22])[CH2:18][CH2:17]2)=N1.Cl>>[CH3:22][N:19]1[CH2:20][CH2:21][C:16]2([C:8]3[C:7](=[CH:12][C:11]4[O:13][CH2:14][O:15][C:10]=4[CH:9]=3)[C:4](=[O:5])[O:23]2)[CH2:17][CH2:18]1Participants
3
Procedure
Treatment of 4-[2-(4,4-dimethyl-2-oxazolin-2-yl)-4,5-methylenedioxyphenyl]-4-hydroxy-1-methylpiperidine with hydrochloric acid by the method described in Example 1d provides 1,3-dihydro-1'-methyl-5,6-methylenedioxyspiro[isobenzofuran-1,4'-piperidine]-3-one.
Sources & evidence
- ORD record
- ord-bc0ffe7a61244094ba9771edc8d9fcf4
- Source dataset
- uspto-grants-1976_10
- Patent number
- US03985889
Reaction notes
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