HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-piperidone → 4-(4-Chloro-alpha-hydroxy-2-tolyl)-4-hydroxy-1-methylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | (2-Bromo-4-chlorophenyl)methanol | HCID 54049764 | — |
| Product | 4-(4-Chloro-alpha-hydroxy-2-tolyl)-4-hydroxy-1-methylpiperidine | HCID 86733528 | — |
Reaction Steps
Reaction of 2-bromo-4-chlorobenzyl alcohol and 1-methyl-4-piperidone by the method described in Example 16a provides 4-(4-chloro-α-hydroxy-2-tolyl)-4-hydroxy-1-methylpiperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985889 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-18f217f0c2c049f6b3a33471238578e6 |
| Source note | uspto-grants-1976_10 |