Hydrochloric Acid → HCID 21506840, compound

HRID 1287918Notes

Reaction equation

HRID 1287918 reaction equation
O[C:2]1([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[CH2:14][OH:15])[CH2:6][CH2:5][N:4]([CH3:7])[CH2:3]1.Cl>>[CH3:7][N:4]1[CH2:5][CH2:6][C:2]2([C:8]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH2:14][O:15]2)[CH2:3]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 21506836HCID 21506836, compound

Product 1

HCID 21506840HCID 21506840, compound

Procedure

Treatment of 3-hydroxy-3-(α-hydroxy-2-tolyl)-1-methylpyrrolidine with hydrochloric acid by the method described in Example 16d provides 1,3-dihydro-1'-methylspiro[isobenzofuran-1,3'-pyrrolidine].

Sources & evidence

ORD record
ord-054b66a1f9ed468dbb596c1af6593e1c
Source dataset
uspto-grants-1976_10
Patent number
US03985889

Reaction notes

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