Hydrochloric Acid → HCID 21503157, compound

HRID 1287948Notes

Reaction equation

HRID 1287948 reaction equation
[SH:1][CH:2]([CH2:5][SH:6])[CH2:3][OH:4].[C:7](Cl)(=[O:19])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].Cl>C1C=CC=CC=1>[C:7]([O:4][CH2:3][CH:2]([SH:1])[CH2:5][SH:6])(=[O:19])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3080DimercaprolHCID 8166Dodecanoyl chloride

Product 1

HCID 21503157HCID 21503157, compoundYield 38.8%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

2,3-Dimercaptopropanol (12.0 g) is dissolved in benzene (75 ml) and thereto is added dropwise lauroyl chloride (21.5 g) with stirring. The mixture is refluxed with stirring for about 3.5 hours until the generation of hydrogen chloride is ceased to evolve. The mixture is then distilled to remove benzene and the resulting residue is distilled to give 2,3-dimercaptopropyl laurate (11.5 g) as a yellow oily substance, b.p. 167° - 175° C/1 mmHg.

Workup

  1. temperatureThe mixture is refluxed
  2. distillationThe mixture is then distilled
  3. customto remove benzene
  4. distillationthe resulting residue is distilled

Sources & evidence

ORD record
ord-ac0e576e27a244e78e1fa0e75ca8f791
Source dataset
uspto-grants-1976_10
Patent number
US03986930

Reaction notes

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