1-Methyl-2-nitro-1H-imidazole-5-carboxaldehyde → HCID 53759317, compound

HRID 1288021Notes

Reaction equation

HRID 1288021 reaction equation
[NH2:1][NH:2][C:3]([NH2:5])=[S:4].[CH3:6][N:7]1[C:11]([CH:12]=O)=[CH:10][N:9]=[C:8]1[N+:14]([O-:16])=[O:15]>O.CO>[CH3:6][N:7]1[C:11]([CH:12]=[N:1][NH:2][C:3]([NH2:5])=[S:4])=[CH:10][N:9]=[C:8]1[N+:14]([O-:16])=[O:15]

Participants

5

Reactant 2

HCID 1003901-Methyl-2-nitro-1H-imidazole-5-carboxaldehydeHCID 2723789Thiosemicarbazide

Product 1

HCID 53759317HCID 53759317, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

A solution of 1.42 g. of thiosemicarbazide in water is added to a solution of 1.8 g. of 1-methyl-2-nitro-5-imidazolecarboxaldehyde in methanol. The solid which precipitates is recovered on the filter. Yield: 2.2 g., m.p. 282°-287° C.

Workup

  1. customThe solid which precipitates
  2. customis recovered on the filter

Sources & evidence

ORD record
ord-d302eb8bbeb34008984672f536bb57fe
Source dataset
uspto-grants-1976_10
Patent number
US03987053

Reaction notes

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