Benzoylhydrazine → HCID 21489341, compound

HRID 1288048Notes

Reaction equation

HRID 1288048 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10](=S)[CH2:9][N:8]=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1.[C:20]([NH:28][NH2:29])(=O)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]3[C:20]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)=[N:28][N:29]=[C:10]3[CH2:9][N:8]=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1

Participants

4

Reactant 2

HCID 11955BenzoylhydrazineHCID 826706Thionordiazepam

Product 1

HCID 21489341HCID 21489341, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
250 °C

Procedure

In the manner given in Example 2, 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione was heated in ethanol with benzoic acid hydrazide and the resulting product heated to 250° C. to give 8-chloro-1,6-diphenyl-4H-s-triazolo[4,3-a]-[1,4]benzodiazepine of melting point 193.5°-194.5° C.

Sources & evidence

ORD record
ord-23a52a64bd864dfeb2d99cf8fc99a708
Source dataset
uspto-grants-1976_10
Patent number
US03987052

Reaction notes

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