Benzoylhydrazine → HCID 21489326, compound

HRID 1288056Notes

Reaction equation

HRID 1288056 reaction equation
[N+:1]([C:4]1[CH:22]=[CH:21][C:7]2[C:8]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])=[N:9][CH2:10][C:11](=S)[NH:12][C:6]=2[CH:5]=1)([O-:3])=[O:2].[C:23]([NH:31][NH2:32])(=O)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>C(O)C>[N+:1]([C:4]1[CH:22]=[CH:21][C:7]2[C:8]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])=[N:9][CH2:10][C:11]3[N:12]([C:23]([C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)=[N:31][N:32]=3)[C:6]=2[CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 11955BenzoylhydrazineHCID 19865803HCID 19865803, compound

Product 1

HCID 21489326HCID 21489326, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
250 °C

Procedure

In the manner given in Example 2, 8-nitro-1,3-dihydro-5-(o-chlorophenyl)-2H-1,4-benzodiazepine-2-thione is heated in ethanol with benzoic acid hydrazide and the resulting product heated to 250° C. to give 9-nitro-1-phenyl-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-4946107c39bf4695a2a57349a0cea3d8
Source dataset
uspto-grants-1976_10
Patent number
US03987052

Reaction notes

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