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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1288059Generated: October 31, 2026

Propionylhydrazine → 10-(propylsulfonyl)-8-methyl-1-ethyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine

https://huagongshe.com/reaction/1288059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropionylhydrazineHCID 79890—
ReactantHCID 19865840HCID 19865840—
SolventEthanolHCID 702—
Product10-(propylsulfonyl)-8-methyl-1-ethyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepineHCID 21489340—

Reaction Conditions

Temperature250 °C

Reaction Steps

In the manner given in Example 2, 9-(propylsulfonyl)-7-methyl-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione is heated in ethanol with propionic acid hydrazide and the resulting product heated to 250° C. to give 10-(propylsulfonyl)-8-methyl-1-ethyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03987052
Source datasetuspto-grants-1976_10
ORD IDord-ca30cdbefd104ac78749255ed773c04d
Source noteuspto-grants-1976_10