1-Bromooctane → HCID 19375100, compound

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Reaction Steps

This phenol is alkylated again by the same method, but using sodium hydride and 1-bromooctane, to provide 1-((2,2-dimethoxyethyl)thio)-4-(octyloxy)benzene as a colorless oil after chromatography (87% yield). By the method of example 2, this is converted into the title compound, obtained as a pale yellow solid, mp 70°-72° after recrystallization from hexane-dichloromethane.

Provenance & Evidence