HCID 68138398, compound → HCID 54323513, compound

HRID 1288134Notes

Reaction equation

HRID 1288134 reaction equation
Cl.[CH2:2]([O:4][C:5]([N:7]1[CH2:21][CH2:20][C:19]2[C:10](=[N:11][C:12]3[CH:13]=[CH:14][CH:15]=[C:16]([N+:23]([O-])=O)[C:17]=3[C:18]=2[CH3:22])[CH2:9][CH2:8]1)=[O:6])[CH3:3]>Cl>[CH2:2]([O:4][C:5]([N:7]1[CH2:21][CH2:20][C:19]2[C:10](=[N:11][C:12]3[CH:13]=[CH:14][CH:15]=[C:16]([NH2:23])[C:17]=3[C:18]=2[CH3:22])[CH2:9][CH2:8]1)=[O:6])[CH3:3]

Participants

3

Reactant 1

HCID 68138398HCID 68138398, compound

Product 1

HCID 54323513HCID 54323513, compoundYield 26%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

10-Amino-1,2,4,5-tetrahydro-11-methyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester was prepared by reducing the corresponding 10-nitro compound (see Example 91) with tin-II-chloride in concentrated hydrochloric acid.

Sources & evidence

ORD record
ord-1aef85345fe5499e876c56c455550d1c
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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