Hydrochloric Acid → HCID 21503555, compound

Participants

Reaction Steps

1,2,4,5-Tetrahydro-5-hydroxy-11-methyl-3H-azepino[4,5-b]quinoline dihydrochloride was prepared from 5-(ethoxycarbonyloxy)-1,2,4,5-tetrahydro-11-methyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester by hydrolysis with 2 N hydrochloric acid for 36 hours at the boiling point. After distilling off the hydrochloric acid, the remaining water was removed by entrainment with benzene, and the raw salt was recrystallized from methanol.

Provenance & Evidence