Isobutyryl chloride → HCID 21503444, compound

HRID 1288173Notes

Reaction equation

HRID 1288173 reaction equation
[CH3:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16][C:3]=12.[C:17](Cl)(=[O:21])[CH:18]([CH3:20])[CH3:19]>>[C:17]([N:14]1[CH2:15][CH2:16][C:3]2[C:4](=[N:5][C:6]3[CH:7]=[CH:8][CH:9]=[CH:10][C:11]=3[C:2]=2[CH3:1])[CH2:12][CH2:13]1)(=[O:21])[CH:18]([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 62325Isobutyryl chlorideHCID 304399911-methyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]quinoline

Product 1

HCID 21503444HCID 21503444, compoundYield 50%

Procedure

3-Isobutyryl-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline was prepared by acylation of 1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline with isobutyryl chloride in pryidine.

Sources & evidence

ORD record
ord-569a481ec2f140468bb4f177f2e40089
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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