HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroacetate → HCID 68139344, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroacetate | HCID 7751 | — |
| Reactant | 11-methyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]quinoline | HCID 3043999 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 68139344 | HCID 68139344 | — |
Reaction Steps
15 ml (141 millimols) of ethyl chloroacetate were added dropwise to a boiling solution of 30 gm (141 millimols) of 1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline in 200 ml of benzene and 20 ml of triethylamine. After filtering off the precipitated triethylamine hydrochloride, the solvent was distilled off, and the residual base was converted into the dihydrochloride in ethanol with ethanolic hydrochloric acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03987047 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-1af9143ccfde4c70ad1cdc82c0610cda |
| Source note | uspto-grants-1976_10 |