Hydrochloric Acid → HCID 68139110, compound

HRID 1288182Notes

Reaction equation

HRID 1288182 reaction equation
C([O:3][C:4](=[O:23])[CH2:5][CH2:6][N:7]1[CH2:21][CH2:20][C:19]2[C:10](=[N:11][C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:17]=3[C:18]=2[CH3:22])[CH2:9][CH2:8]1)C.[ClH:24]>>[ClH:24].[ClH:24].[CH3:22][C:18]1[C:17]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[N:11]=[C:10]2[CH2:9][CH2:8][N:7]([CH2:6][CH2:5][C:4]([OH:23])=[O:3])[CH2:21][CH2:20][C:19]=12

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 53908345HCID 53908345, compound

Product 1

HCID 68139110HCID 68139110, compoundYield 76%

Procedure

3-[1,2,4,5-Tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline-3-yl]propionic acid dihydrochloride was prepared by hydrolysis of 3-[1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline-3-yl]propionic acid ethyl ester with 2 N hydrochloric acid at reflux temperature.

Workup

  1. temperatureat reflux temperature

Sources & evidence

ORD record
ord-834692389f864f77afc069acaf70af4b
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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