Phenacylamine → HCID 21503631, compound

Participants

Reaction Steps

2,3,4,5-tetrahydro-11-methyl-2-propyl-1H-azepino[4,3-b]quinoline and their dihydrochlorides were prepared from 4-ethoxy-1,2,6,7-tetrahydro-1-propyl-5H-azepine and 2amino-acetophenone analogous to Example 217. Yield of the dihydrochloride of the [4,5-b]-isomer: 15% of theory; m.p. 245-246° C. Yield of the dihydrochloride of the [4,3-b]-isomer: 10% of theory; m.p. 282° C.

Provenance & Evidence