Hydrochloric Acid → HCID 135556900, compound

HRID 1288200Notes

Reaction equation

HRID 1288200 reaction equation
C(OC([N:6]1[CH2:20][CH2:19][C:18]2[C:9](=[N:10][C:11]3[CH:12]=[CH:13][CH:14]=[C:15]([OH:22])[C:16]=3[C:17]=2[CH3:21])[CH2:8][CH2:7]1)=O)C.[ClH:23]>>[ClH:23].[ClH:23].[OH:22][C:15]1[C:16]2[C:17]([CH3:21])=[C:18]3[CH2:19][CH2:20][NH:6][CH2:7][CH2:8][C:9]3=[N:10][C:11]=2[CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 136354612HCID 136354612, compound

Product 1

HCID 135556900HCID 135556900, compoundYield 72%

Procedure

10-Hydroxy-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline dihydrochloride was prepared by hydrolysis of 10-hydroxy-1,2,4,5-tetrahydro-11-methyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester in concentrated hydrochloric acid. Yield: 72% of theory; m.p. >300° C.

Sources & evidence

ORD record
ord-f2bf0cdf017040b392951ae8de75f400
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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