Hydrochloric Acid → HCID 135556902, compound

HRID 1288201Notes

Reaction equation

HRID 1288201 reaction equation
C(OC([N:6]1[CH2:20][CH2:19][C:18]2[C:9](=[N:10][C:11]3[CH:12]=[C:13]([OH:22])[CH:14]=[CH:15][C:16]=3[C:17]=2[CH3:21])[CH2:8][CH2:7]1)=O)C.[ClH:23]>>[ClH:23].[ClH:23].[OH:22][C:13]1[CH:14]=[CH:15][C:16]2[C:17]([CH3:21])=[C:18]3[CH2:19][CH2:20][NH:6][CH2:7][CH2:8][C:9]3=[N:10][C:11]=2[CH:12]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 136354613HCID 136354613, compound

Product 1

HCID 135556902HCID 135556902, compoundYield 34%

Procedure

8-Hydroxy-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline dihydrochloride was prepared by hydrolysis of 8-hydroxy-1,2,4,5-tetrahydro-11-methyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester in concentrated hydrochloric acid. Yield: 34% of theory; m.p. 245° C (decomp.).

Sources & evidence

ORD record
ord-dcdcb58590f24a0eb8b3638792be205d
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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