HuagongsheHuagongshe Chemistry Print Report · For research reference only
11-methyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]quinoline → 3-Carbamoyl-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 11-methyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]quinoline | HCID 3043999 | — |
| Reactant | Potassium cyanate | HCID 11378442 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Carbamoyl-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline | HCID 21503667 | — |
Reaction Steps
3.3 gm (11.6 millimols) of 1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline were reacted with 0.04 gm (11.6 millimols) of potassium cyanate at room temperature in 50 ml of water. After 4 to 6 hours, the reaction product crystallized out. Yield: 1 gm (34% of theory); m.p. 215° C (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03987047 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-8e0616792a9f4887b08ff0f6ca083dea |
| Source note | uspto-grants-1976_10 |