HCID 54274069, compound → HCID 21503565, compound

HRID 1288205Notes

Reaction equation

HRID 1288205 reaction equation
C([NH:9][C:10]([N:12]1[CH2:26][CH2:25][C:24]2[C:15](=[N:16][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][C:22]=3[C:23]=2[CH3:27])[CH2:14][CH2:13]1)=[S:11])(=O)C1C=CC=CC=1>[OH-].[Na+]>[C:10]([N:12]1[CH2:26][CH2:25][C:24]2[C:15](=[N:16][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][C:22]=3[C:23]=2[CH3:27])[CH2:14][CH2:13]1)(=[S:11])[NH2:9]

Participants

3

Reactant 1

HCID 54274069HCID 54274069, compound

Product 1

HCID 21503565HCID 21503565, compoundYield 36%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

3-Thiocarbamoyl-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline was prepared by hydrolysis of 3-(benzamido-thiocarbonyl)-1,2,4,5-tetrahydro-11-methyl-azepino[4,5-b]quinoline (m.p. 175° C) in 2 N sodium hydroxide at room temperature. Yield: 36 % of theory; m.p. 218° C.

Sources & evidence

ORD record
ord-a46c1d9e48a24f69887fc62543eebd2c
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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