Hydrochloric Acid → HCID 12270048, compound

HRID 1288239Notes

Reaction equation

HRID 1288239 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]#[N:11])=[CH:5][CH:4]=1.[CH2:12]([OH:14])[CH3:13]>CCOCC>[ClH:2].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10](=[NH:11])[O:14][CH2:12][CH3:13])=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 2415824-Chlorobenzyl cyanide

Product 1

HCID 12270048HCID 12270048, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Dry hydrogen chloride was passed into a mixture of 4-chlorophenylacetonitrile (50.5 g.) and dry ethanol (16.1 g., 20.1 ml.) until a weight increase of 14.6 g. was obtained. The mixture was allowed to stand at room temperature for 3 days; the resulting crystalline mass was broken up, digested thoroughly with dry ether, filtered, and dried in vacuo to give ethyl 4-chlorophenylacetimidate hydrochloride.

Workup

  1. temperatureincrease of 14.6 g
  2. customwas obtained
  3. filtrationfiltered
  4. customdried in vacuo

Sources & evidence

ORD record
ord-29ece5f21cbf408480ff50bbe552e8aa
Source dataset
uspto-grants-1976_10
Patent number
US03987158

Reaction notes

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