Hydrogen Sulfide → HCID 21504219, compound

HRID 1288245Notes

Reaction equation

HRID 1288245 reaction equation
[SH2:1].[CH3:2][C:3]1[CH:4]=[C:5]([CH2:10][C:11]#[N:12])[CH:6]=[CH:7][C:8]=1[CH3:9].C(N(CC)CC)C>N1C=CC=CC=1>[CH3:2][C:3]1[CH:4]=[C:5]([CH2:10][C:11]([NH2:12])=[S:1])[CH:6]=[CH:7][C:8]=1[CH3:9]

Participants

5

Reactant 3

HCID 402Hydrogen SulfideHCID 8471TriethylamineHCID 764012-(3,4-Dimethylphenyl)acetonitrile

Product 1

HCID 21504219HCID 21504219, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The 3,4-dimethylphenyl(thioacetamide) was prepared by passing a slow stream of hydrogen sulphide through a solution of 3,4-dimethylphenylacetonitrile (56.6 g.) in pyridine (60 ml.) and triethylamine (39.4 g.) during 12 hours. The reaction mixture was evaporated under reduced pressure and the residue was recrystallised from a mixture of benzene and light petroleum (b.p. 60°-80°) to give 3,4-dimethylphenyl (thioacetamide), m.p. 91°-94°.

Workup

  1. customThe 3,4-dimethylphenyl(thioacetamide) was prepared
  2. customduring 12 hours
  3. customThe reaction mixture was evaporated under reduced pressure
  4. customthe residue was recrystallised from a mixture of benzene and light petroleum (b.p. 60°-80°)

Sources & evidence

ORD record
ord-cc09d06590594a4bb9f0caedb4f83aa2
Source dataset
uspto-grants-1976_10
Patent number
US03987158

Reaction notes

Loading…