Hydrochloric Acid → 4-Amino-3-nitrobenzene-1-sulfonamide

HRID 1288314Notes

Reaction equation

HRID 1288314 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[CH:7][C:6]=1[N+:15]([O-:17])=[O:16])(=O)C.Cl>>[NH2:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[CH:7][C:6]=1[N+:15]([O-:17])=[O:16]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 142266934-Acetylamino-3-nitrobenzenesulfonamide

Product 1

HCID 27743884-Amino-3-nitrobenzene-1-sulfonamide

Procedure

7.5 G. of 4-acetylamino-3-nitrobenzenesulfonamide is dissolved in 60 ml. of 6N hydrochloric acid and refluxed for 2 hours. The reaction mixture is cooled, filtered, and the solid material washed with water and dried. The dried 4-amino-3-nitrobenzenesulfonamide has a m.p. of 280°-210° C. and is of sufficient purity for use in the next step.

Workup

  1. temperatureThe reaction mixture is cooled
  2. filtrationfiltered
  3. washthe solid material washed with water
  4. customdried

Sources & evidence

ORD record
ord-d021e36181714ed4a50e7e56439e489e
Source dataset
uspto-grants-1976_10
Patent number
US03987199

Reaction notes

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