反应详情

The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the ethyl 7-bromoheptanoate is replaced by an equimolar amount of methyl 3-methyl-7-iodoheptanoate. The product of Step A is methyl 7-{N-[4-(2-tetrahydropyranyloxy)nonyl]acetamido}-3-methylheptanoate. The subsequent step yields 7-[N-(4-hydroxynonyl)acetamido]-3-methylheptanoic acid (B).

1. customThe synthesis of this compound