HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 7-bromoheptanoate → ethyl 7-[N-(4-acetoxynonyl)-acrylamido]heptanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 7-bromoheptanoate | HCID 122490 | — |
| Reactant | Methyl 3-methyl-7-iodoheptanoate | HCID 20322201 | — |
| Reactant | methyl 7-{N-[4-(2-tetrahydropyranyloxy)nonyl]acetamido}-3-methylheptanoate | HCID 21503938 | — |
| Product | ethyl 7-[N-(4-acetoxynonyl)-acrylamido]heptanoate | HCID 21503957 | — |
Reaction Steps
The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the ethyl 7-bromoheptanoate is replaced by an equimolar amount of methyl 3-methyl-7-iodoheptanoate. The product of Step A is methyl 7-{N-[4-(2-tetrahydropyranyloxy)nonyl]acetamido}-3-methylheptanoate. The subsequent step yields 7-[N-(4-hydroxynonyl)acetamido]-3-methylheptanoic acid (B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03987091 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-47b6dc8f0c66480091909132558d028b |
| Source note | uspto-grants-1976_10 |