Hydrochloric Acid → HCID 136354630, compound

Participants

Reaction Steps

To a suspension of 9.18 g. (3.4 × 10-2 mole) of 7-Nitro-6-methoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-one hydrochloride in 95% ethanol (300 ml.) is added 10 ml. of concentrated hydrochloric acid and 0.45 g. of 10% Pd/C catalyst. The mixture is placed on a Paar hydrogenator, shaken until theoretical hydrogen is absorbed, removed and water (150 ml.) added to effect dissolution of the precipitate. The mixture is filtered under suction, the catalyst washed with 95% ethanol and the mixture evaporated to dryness yielding the title product as a yellow powder.

Provenance & Evidence