HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropenyl acetate → 2-Acetyl-8-amino-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropenyl acetate | HCID 7916 | — |
| Reactant | 8-Amino-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline | HCID 21393824 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Acetyl-8-amino-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline | HCID 21393812 | — |
Reaction Steps
8-Amino-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline, prepared as in Example 17, is treated with one molar equivalent of isopropenyl acetate in refluxing ethyl acetate by the procedure of Example 15 to give 2-acetyl-8-amino-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03988339 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-25e2f675175644ee9a0be07857d85628 |
| Source note | uspto-grants-1976_10 |