HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 8-Methylsulfamoyl-1,2,3,4-tetrahydroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 15896351 | HCID 15896351 | — |
| Reactant | 1,2,3,4-Tetrahydroisoquinolin-8-amine | HCID 20523209 | — |
| Product | 8-Methylsulfamoyl-1,2,3,4-tetrahydroisoquinoline | HCID 21393875 | — |
Reaction Steps
By the procedure of Example 15, 8-amino-1,2,3,4-tetrahydroisoquinoline is converted to 2-acetyl-8-chlorosulfonyl-1,2,3,4-tetrahydroisoquinoline. Reacting with methylamine by the procedure of Example 27 and hydrolyzing to remove the 2-acetyl group gives 8-methylsulfamoyl-1,2,3,4-tetrahydroisoquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03988339 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-c0070aafdfae48f690613df069eb37d2 |
| Source note | uspto-grants-1976_10 |