反应详情

A suspension of 28.5 g. (0.098 mole) of 2-(4-bromophenethyl)-benzyl alcohol in 150 ml. of 48% hydrobromic acid is stirred at reflux for 3 hours. The cooled two-phase mixture is extracted with benzene. Evaporation of the washed and dried benzene extract under reduced pressure leaves the product as the residual solid, m.p. 63°-75° C. Recrystallization from hexane affords purified material, m.p. 76°-77.5° C. A sample for analysis melts at 76.5°-78° C. after further recrystallization from hexane.

1. additionA suspension of 28.5 g
2. temperatureat reflux for 3 hours
3. extractionThe cooled two-phase mixture is extracted with benzene
4. customEvaporation of the
5. washwashed
6. extractiondried benzene extract under reduced pressure
7. customleaves the product as the residual solid, m.p. 63°-75° C
8. customRecrystallization from hexane
9. customaffords
10. custompurified material, m.p. 76°-77.5° C
11. customA sample for analysis melts at 76.5°-78° C. after further recrystallization from hexane