참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | P-Cresol | HCID 2879 | — |
| 반응물 | Acetic acid, benzoyldiazo-, ethyl ester | HCID 605325 | — |
| 촉매 | Acetic acid, rhodium(2+) salt | HCID 21674 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | Ethyl alpha-(4-Methylphenyl)benzoylacetate | HCID 54208493 | 26.1% |
반응 단계
A mixture of 7.66 g of ethyl α-diazobenzoylacetate, 3.8 g of p-cresol and 150 mg of rhodium(II) acetate in 40 cc of carbon tetrachloride was stirred at a temperature of 40-50° C. for 2 hours. After cooling, the insoluble materials were filtered off and the solvent was distilled off. The crude product thus obtained was purified by a silica gel column chromatography (eluent: chloroform/hexane=1/2) to obtain 2.59 g of compound E. Yield: 24.7%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05464863 |
|---|
| 출처 데이터셋 | uspto-grants-1995_11 |
|---|
| ORD ID | ord-cc3e28ef97e743c19827d3205278a575 |
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| 출처 메모 | uspto-grants-1995_11 |
|---|
